ABSTRACT
Objective To analyze the data of suspected adverse events following immunization (AEFI) in Xiaogan City from 2012 to 2017, and to evaluate the sensitivity of the monitoring system and the safety and quality of vaccine use. Methods The AEFI surveillance information system of China Immunization Program was used to derive the AEFI report case data from 2012 to 2017 in Xiaogan City. The descriptive methods were used for epidemiological analysis. Results There were 2 457 cases of AEFI reported in Xiaogan City from 2012 to 2017. The incidence rate of reported AEFI was 22.37 / 100 000. Among them, the incidence rate of the general reaction reported was 20.04 / 100 000, and the reactions were mainly fever, redness, and induration. The abnormal reaction report rate was 1.98/100 000, mainly with allergic skin rashes. There were no accidents caused by the quality of the vaccine and negligence of related persnonnels. There were case reports every month, but there was a big difference in the time distribution of case reports throughout the year (χ2= 54.86, P=0.01). The most reported cases were from April to June, and there were obvious differences in the number of reported cases in different counties (cities and districts) (χ2=29.99, P=0.02). The ratio of male to female was 1.5:1. There were 2 025 cases in the age group of 0~3, accounting for 82.42%. Conclusion The sensitivity of AEFI surveillance in Xiaogan City increased year by year, and the safety of vaccination was good. It is necessary to further strengthen the monitoring of AEFI among young children, especially within 24 hours of vaccination.